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Image Search Results
Journal: Journal of Toxicologic Pathology
Article Title: Evaluation of the teratogenic effects of three traditional Chinese medicines, Si Jun Zi Tang, Liu Jun Zi Tang and Shenling Baizhu San, during zebrafish pronephros development
doi: 10.1293/tox.2013-0045
Figure Lengend Snippet: CMP-induced kidney malformation phenotypes are dose dependent. Morphological changes of Tg( wt1b :GFP) embryos after exposure to 25, 250, and 1,250 ng/mL of CMP (SJZT, LJZT, SLBS). Phenotype percentages of zebrafish embryos after CMP treatments using exposure methods I, II, and III (A, B, C). All photos were taken from a dorsal view at the developmental stage of 48 hpf. (D) The Tukey-Kramer HSD (honestly significant difference) test reported the marginal mean malformation rates and corresponding 95% confidence intervals for combinations of the method and CMP groups, which were adjusted for dose effect. Two group means are significantly different if their intervals are disjoint; and are not significantly different if their intervals overlap. An arrow, star and triangle indicate the defective sites in gl, pt; and pd, respectively. Scale bar: 40 μm.
Article Snippet: All embryos were observed under a microscope (DM 2500, Leica) equipped with Nomarski differential interference contrast optics and a fluorescent module having a
Techniques: